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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
10.91
Human Site:
S288
Identified Species:
17.14
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S288
S
Q
A
L
Q
Q
T
S
A
T
D
I
S
S
A
Chimpanzee
Pan troglodytes
XP_511025
426
45548
G273
L
T
P
T
A
V
P
G
S
A
E
V
Q
G
M
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S288
S
Q
T
L
Q
Q
T
S
A
T
E
I
S
S
A
Dog
Lupus familis
XP_853833
304
33793
L250
Q
Q
T
P
A
T
D
L
S
S
A
G
S
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
P278
S
Q
T
F
Q
Q
T
P
A
A
E
V
S
S
G
Rat
Rattus norvegicus
Q62814
300
33206
S249
T
P
A
T
E
I
S
S
G
S
I
S
G
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
P175
Q
T
P
V
S
N
T
P
S
G
A
I
S
G
D
Chicken
Gallus gallus
Q90977
403
43534
M347
S
L
S
P
L
A
S
M
D
T
L
L
E
H
G
Frog
Xenopus laevis
NP_001086706
375
40890
E250
H
S
T
I
S
N
A
E
S
Q
D
C
P
T
G
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
T250
C
Q
S
P
S
T
T
T
T
S
N
T
A
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
T606
I
A
A
G
S
S
T
T
A
T
T
T
L
N
S
Honey Bee
Apis mellifera
XP_624285
300
34327
D249
L
R
D
V
S
T
S
D
I
A
Q
K
D
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
L298
S
P
E
S
L
K
D
L
Q
T
D
M
L
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
S369
P
S
D
A
P
S
S
S
Q
D
I
S
G
M
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
D405
H
P
H
P
Q
P
G
D
T
S
D
L
N
Y
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
0
86.6
13.3
N.A.
53.3
13.3
N.A.
20
13.3
6.6
13.3
N.A.
26.6
0
N.A.
20
P-Site Similarity:
100
20
93.3
33.3
N.A.
66.6
40
N.A.
33.3
33.3
26.6
46.6
N.A.
46.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
20
7
14
7
7
0
27
20
14
0
7
0
14
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
14
0
0
0
14
14
7
7
27
0
7
7
14
% D
% Glu:
0
0
7
0
7
0
0
7
0
0
20
0
7
0
7
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
7
0
0
7
7
7
7
0
7
14
14
20
% G
% His:
14
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
7
0
7
0
0
7
0
14
20
0
14
7
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% K
% Leu:
14
7
0
14
14
0
0
14
0
0
7
14
14
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
14
% M
% Asn:
0
0
0
0
0
14
0
0
0
0
7
0
7
7
0
% N
% Pro:
7
20
14
27
7
7
7
14
0
0
0
0
7
0
0
% P
% Gln:
14
34
0
0
27
20
0
0
14
7
7
0
7
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
14
14
7
34
14
27
27
27
27
0
14
34
20
14
% S
% Thr:
7
14
27
14
0
20
40
14
14
34
7
14
0
7
7
% T
% Val:
0
0
0
14
0
7
0
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _